Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
ppdKPyruvate, phosphate dikinase. (863 aa)    
Predicted Functional Partners:
nifJ
Pyruvate synthase.
    
 0.961
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.923
EES65082.1
NAD-dependent malic enzyme.
  
 
 0.920
pflB
Formate C-acetyltransferase.
    
 0.919
EES64963.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin).
    
 0.913
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.910
pyk-2
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.910
EES63527.1
2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family.
    
 0.909
EES63528.2
2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family.
    
 0.908
EES64962.1
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein.
    
 0.906
Your Current Organism:
Fusobacterium varium
NCBI taxonomy Id: 469618
Other names: F. varium ATCC 27725, Fusobacterium varium ATCC 27725
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