Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
pflAPyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (243 aa)    
Predicted Functional Partners:
pflB
Formate C-acetyltransferase.
  
 0.984
nifJ
Pyruvate synthase.
     
 0.739
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
 
  
 0.613
EES62596.1
Rubredoxin.
  
  
 0.601
tsaD
Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.590
EES63688.1
Acetaldehyde dehydrogenase (acetylating).
 
  
 0.550
hymB
Protein HymB.
     
 0.471
EES62804.1
Putative NADPH-dependent butanol dehydrogenase.
  
  
 0.403
EES64805.1
Alcohol dehydrogenase, iron-dependent.
  
  
 0.403
fucO
Lactaldehyde reductase.
  
  
 0.403
Your Current Organism:
Fusobacterium varium
NCBI taxonomy Id: 469618
Other names: F. varium ATCC 27725, Fusobacterium varium ATCC 27725
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