STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa)    
Predicted Functional Partners:
purD
KEGG: bth:BT3253 3.9e-178 phosphoribosylamine--glycine ligase K01945; COG: COG0151 Phosphoribosylamine-glycine ligase; Psort location: Cytoplasmic, score: 8.96; Belongs to the GARS family.
 
 0.998
purL
Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
  
 0.997
purC
KEGG: bth:BT4217 5.0e-153 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; COG: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SAICAR synthetase family.
 
 
 0.992
purN
Putative phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 
 0.982
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
 
 0.980
EDV00461.1
Hypothetical protein; KEGG: bfr:BF0911 2.0e-190 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.963
purB
KEGG: bth:BT3871 4.8e-212 adenylosuccinate lyase K01756; COG: COG0015 Adenylosuccinate lyase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.952
EDV00374.1
KEGG: bth:BT4582 4.5e-216 amidophosphoribosyltransferase precursor K00764; COG: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; Psort location: Cytoplasmic, score: 8.96; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.946
purH
Putative phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: bfr:BF4101 5.0e-224 phosphoribosylaminoimidazole carboxy formyl formyltransferase K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.96.
 
  
 0.929
EDV01669.1
Class II glutamine amidotransferase; KEGG: chu:CHU_2612 9.0e-163 purF; amidophosphoribosyltransferase K00764; COG: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.887
Your Current Organism:
Bacteroides coprocola
NCBI taxonomy Id: 470145
Other names: B. coprocola DSM 17136, Bacteroides coprocola DSM 17136, Bacteroides coprocola M16, Bacteroides coprocola str. DSM 17136, Bacteroides coprocola strain DSM 17136
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