node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ftsI | ftsI-2 | TN98_04225 | TN98_05095 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.953 |
ftsI | ftsL | TN98_04225 | TN98_05090 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.847 |
ftsI | ftsN | TN98_04225 | TN98_01460 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.841 |
ftsI | ftsQ | TN98_04225 | TN98_05140 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.919 |
ftsI | ftsW | TN98_04225 | TN98_05120 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.985 |
ftsI | mrcB | TN98_04225 | TN98_05435 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Bifunctional glycosyl transferase/transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.934 |
ftsI | mrdA | TN98_04225 | TN98_06915 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.908 |
ftsI | mrdB | TN98_04225 | TN98_06910 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.974 |
ftsI | murE | TN98_04225 | TN98_05100 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.891 |
ftsI | murG | TN98_04225 | TN98_05125 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.804 |
ftsI-2 | ftsI | TN98_05095 | TN98_04225 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.953 |
ftsI-2 | ftsL | TN98_05095 | TN98_05090 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.967 |
ftsI-2 | ftsN | TN98_05095 | TN98_01460 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.841 |
ftsI-2 | ftsQ | TN98_05095 | TN98_05140 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.969 |
ftsI-2 | ftsW | TN98_05095 | TN98_05120 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.998 |
ftsI-2 | mrcB | TN98_05095 | TN98_05435 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Bifunctional glycosyl transferase/transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.935 |
ftsI-2 | mrdA | TN98_05095 | TN98_06915 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.965 |
ftsI-2 | mrdB | TN98_05095 | TN98_06910 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.980 |
ftsI-2 | murE | TN98_05095 | TN98_05100 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.984 |
ftsI-2 | murG | TN98_05095 | TN98_05125 | Cell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.971 |