STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (265 aa)    
Predicted Functional Partners:
thiD
Catalyzes the formation hydroxymethylpyrimidine phosphate from hydroxymethylpyrimidine and the formation of of 4-amino-2-methyl-5-diphosphomethylpyrimidine from hydroxymethylpyrimidine phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.991
KKB03009.1
Thiaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.904
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 
 0.852
thiS
Thiamin biosynthesis protein sulfur carrier ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.773
thiL
Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
    
 0.636
KKB04935.1
Allantoin permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.449
tbpA
Thiamine ABC transporter substrate-binding protein; Part of the thiamine and TPP transport system tbpA-thiPQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.419
KKB05154.1
Sulfonate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine-cytosine permease (2.A.39) family.
  
    0.405
KKB04001.1
Cobalamin biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.405
Your Current Organism:
Pantoea anthophila
NCBI taxonomy Id: 470931
Other names: LMG 2558, LMG:2558, P. anthophila, Pantoea anthophila Brady et al. 2009, Pantoea sp. LMG 2558, Pantoea sp. LMG 2560, strain BD 871
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