node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KKB02959.1 | ahpC | TN98_18300 | TN98_13800 | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.750 |
KKB02959.1 | ahpF | TN98_18300 | TN98_13795 | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. | Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.452 |
KKB02959.1 | katE | TN98_18300 | TN98_10230 | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. | Hydroperoxidase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.953 |
KKB02959.1 | katG | TN98_18300 | TN98_13345 | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. | Peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.652 |
KKB02959.1 | sodA | TN98_18300 | TN98_02385 | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.654 |
KKB02959.1 | trxB | TN98_18300 | TN98_08035 | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. | Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.708 |
ahpC | KKB02959.1 | TN98_13800 | TN98_18300 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. | 0.750 |
ahpC | ahpF | TN98_13800 | TN98_13795 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
ahpC | bcsC | TN98_13800 | TN98_02555 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.538 |
ahpC | dps | TN98_13800 | TN98_07755 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | DNA starvation/stationary phase protection protein Dps; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction; Belongs to the Dps family. | 0.731 |
ahpC | katE | TN98_13800 | TN98_10230 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Hydroperoxidase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.761 |
ahpC | katG | TN98_13800 | TN98_13345 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.432 |
ahpC | sodA | TN98_13800 | TN98_02385 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.755 |
ahpC | trxA | TN98_13800 | TN98_02620 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. | 0.581 |
ahpC | trxB | TN98_13800 | TN98_08035 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
ahpC | trxC | TN98_13800 | TN98_15665 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. | 0.477 |
ahpF | KKB02959.1 | TN98_13795 | TN98_18300 | Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. | 0.452 |
ahpF | ahpC | TN98_13795 | TN98_13800 | Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.998 |
ahpF | bcsC | TN98_13795 | TN98_02555 | Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
ahpF | dps | TN98_13795 | TN98_07755 | Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA starvation/stationary phase protection protein Dps; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction; Belongs to the Dps family. | 0.537 |