STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpXClp protease ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (423 aa)    
Predicted Functional Partners:
clpP
Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 0.995
ALV92176.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.937
ALV93677.1
Clp protease ClpP; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.936
ALV94273.1
Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.923
ALV91544.1
Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family.
 
 
 0.901
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
   
 0.894
lon
DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
 0.871
ALV93675.1
GltA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.829
atpD
ATP synthase F0F1 subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
    
 0.755
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.741
Your Current Organism:
Pantoea vagans
NCBI taxonomy Id: 470934
Other names: BCC 105, LMG 24199, LMG:24199, P. vagans, Pantoea sp. BCC002, Pantoea sp. BCC004, Pantoea sp. BCC006, Pantoea sp. BCC067, Pantoea sp. BCC072, Pantoea sp. BCC075, Pantoea sp. BCC079, Pantoea sp. BCC081, Pantoea sp. BCC082, Pantoea sp. BCC107, Pantoea sp. BCC208, Pantoea sp. BCC427, Pantoea sp. BD 502, Pantoea sp. BD502, Pantoea sp. LMG 24195, Pantoea sp. LMG 24196, Pantoea sp. LMG 24199, Pantoea sp. LMG 24201, Pantoea vagans Brady et al. 2009, strain BD 765, strain R-21566
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.