node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALV93197.1 | ALV93675.1 | LK04_14050 | LK04_16640 | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.889 |
ALV93197.1 | dxr | LK04_14050 | LK04_14940 | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). | 0.547 |
ALV93197.1 | purL | LK04_14050 | LK04_04070 | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.591 |
ALV93197.1 | topA | LK04_14050 | LK04_08230 | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.641 |
ALV93197.1 | uppS | LK04_14050 | LK04_14935 | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | UDP pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.856 |
ALV93361.1 | ALV93675.1 | LK04_14925 | LK04_16640 | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
ALV93361.1 | ALV94273.1 | LK04_14925 | LK04_01310 | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.855 |
ALV93361.1 | cdsA | LK04_14925 | LK04_14930 | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. | 0.953 |
ALV93361.1 | dxr | LK04_14925 | LK04_14940 | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). | 0.784 |
ALV93361.1 | frr | LK04_14925 | LK04_14945 | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.724 |
ALV93361.1 | purL | LK04_14925 | LK04_04070 | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.923 |
ALV93361.1 | topA | LK04_14925 | LK04_08230 | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.899 |
ALV93361.1 | uppS | LK04_14925 | LK04_14935 | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.958 |
ALV93675.1 | ALV93197.1 | LK04_16640 | LK04_14050 | GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 0.889 |
ALV93675.1 | ALV93361.1 | LK04_16640 | LK04_14925 | GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
ALV93675.1 | ALV94273.1 | LK04_16640 | LK04_01310 | GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
ALV93675.1 | cdsA | LK04_16640 | LK04_14930 | GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. | 0.840 |
ALV93675.1 | dxr | LK04_16640 | LK04_14940 | GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). | 0.923 |
ALV93675.1 | frr | LK04_16640 | LK04_14945 | GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.993 |
ALV93675.1 | purL | LK04_16640 | LK04_04070 | GltA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.818 |