STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (319 aa)    
Predicted Functional Partners:
ACS24055.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: afl:Aflv_1525 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.975
ACS25378.1
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; KEGG: gka:GK2739 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.975
ACS24056.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: gtn:GTNG_1156 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
  
 
 0.939
ACS23841.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.931
ACS24212.1
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: gka:GK1440 malic enzyme.
  
 0.929
ACS24647.1
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: gtn:GTNG_1385 malate dehydrogenase (malic enzyme).
  
 0.929
ACS23816.1
PFAM: Transketolase central region; Transketolase domain protein; KEGG: gka:GK1059 dehydrogenase E1 component, beta subunit (lipoamide).
   
 0.919
ACS25008.1
PFAM: Transketolase central region; Transketolase domain protein; KEGG: gka:GK2377 branched-chain alpha-keto acid dehydrogenase E1 component beta chain (2-oxoisovalerate dehydrogenase beta subunit).
   
 0.919
ACS25818.1
PFAM: Transketolase central region; Transketolase domain protein; KEGG: gka:GK3216 pyruvate dehydrogenase E1 (lipoamide) beta subunit.
   
 0.919
ACS26028.1
KEGG: afl:Aflv_2793 pyruvate-formate lyase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
   
 
 0.918
Your Current Organism:
Geobacillus sp. WCH70
NCBI taxonomy Id: 471223
Other names: G. sp. WCH70
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