STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCHypothetical protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (259 aa)    
Predicted Functional Partners:
proB
Hypothetical protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.931
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.817
KPV45327.1
Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
 0.756
KPV43613.1
Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.739
KPV44921.1
Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.665
KPV43392.1
Proline iminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
    
  0.632
KPV45395.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.610
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
     
 0.604
KPV42966.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.575
pepA
Hypothetical protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
    
  0.566
Your Current Organism:
Alicyclobacillus ferrooxydans
NCBI taxonomy Id: 471514
Other names: A. ferrooxydans, Alicyclobacillus ferrooxydans Jiang et al. 2008, CGMCC 1.6357, DSM 22381, JCM 15090, strain TC-34
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