STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALC57_17854Putative tyrosyl-DNA phosphodiesterase. (441 aa)    
Predicted Functional Partners:
ALC57_07123
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.890
ALC57_09564
DNA ligase.
   
 
 0.830
ALC57_13848
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    
 
 0.806
ALC57_03361
Aprataxin and PNK-like factor.
    
 
 0.791
ALC57_09771
ATP-dependent DNA helicase 2 subunit 1.
     
 0.737
ALC57_16093
X-ray repair cross-complementing protein 5.
    
 0.701
ALC57_16092
Uncharacterized protein.
    
 0.701
ALC57_09406
DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family.
     
 0.697
ALC57_00810
DNA repair endonuclease XPF.
   
 
 0.694
ALC57_04719
DNA repair endonuclease XPF.
   
 
 0.694
Your Current Organism:
Trachymyrmex cornetzi
NCBI taxonomy Id: 471704
Other names: T. cornetzi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.