STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALC57_02311Signal transducing adapter molecule 1. (533 aa)    
Predicted Functional Partners:
ALC57_14243
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
   
0.996
ALC57_04371
STAM-binding protein-like A.
    
 0.992
ALC57_11889
Targeting protein for Xklp2.
   
 0.990
ALC57_07967
Dual specificity mitogen-activated protein kinase kinase dSOR1; Belongs to the protein kinase superfamily.
    
 0.987
ALC57_08433
Zinc finger FYVE domain-containing protein 1.
   
 0.984
ALC57_03647
Uncharacterized protein.
   
 0.984
ALC57_17622
Polyubiquitin-A.
    
 0.982
ALC57_18827
Tyrosine-protein phosphatase non-receptor type 23.
   
 0.982
ALC57_16109
Ubiquitin-60S ribosomal protein L40.
    
 0.975
ALC57_09793
Intersectin-1.
    
 0.972
Your Current Organism:
Trachymyrmex cornetzi
NCBI taxonomy Id: 471704
Other names: T. cornetzi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.