node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TGRD_139 | TGRD_165 | TGRD_139 | TGRD_165 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Carbamoyl-phosphate synthase arginine-specific large chain. | 0.983 |
TGRD_139 | carA | TGRD_139 | TGRD_163 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | 0.982 |
TGRD_139 | pyrB | TGRD_139 | TGRD_748 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.623 |
TGRD_139 | pyrC | TGRD_139 | TGRD_747 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.919 |
TGRD_165 | TGRD_139 | TGRD_165 | TGRD_139 | Carbamoyl-phosphate synthase arginine-specific large chain. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.983 |
TGRD_165 | TGRD_742 | TGRD_165 | TGRD_742 | Carbamoyl-phosphate synthase arginine-specific large chain. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | 0.946 |
TGRD_165 | carA | TGRD_165 | TGRD_163 | Carbamoyl-phosphate synthase arginine-specific large chain. | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | 0.999 |
TGRD_165 | glmS | TGRD_165 | TGRD_212 | Carbamoyl-phosphate synthase arginine-specific large chain. | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.905 |
TGRD_165 | purF | TGRD_165 | TGRD_257 | Carbamoyl-phosphate synthase arginine-specific large chain. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.954 |
TGRD_165 | purQ | TGRD_165 | TGRD_752 | Carbamoyl-phosphate synthase arginine-specific large chain. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.897 |
TGRD_165 | pyrB | TGRD_165 | TGRD_748 | Carbamoyl-phosphate synthase arginine-specific large chain. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
TGRD_165 | pyrC | TGRD_165 | TGRD_747 | Carbamoyl-phosphate synthase arginine-specific large chain. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.994 |
TGRD_165 | pyrD | TGRD_165 | TGRD_743 | Carbamoyl-phosphate synthase arginine-specific large chain. | Dihydroorotate dehydrogenase catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.971 |
TGRD_165 | pyrE | TGRD_165 | TGRD_741 | Carbamoyl-phosphate synthase arginine-specific large chain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.987 |
TGRD_742 | TGRD_165 | TGRD_742 | TGRD_165 | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Carbamoyl-phosphate synthase arginine-specific large chain. | 0.946 |
TGRD_742 | carA | TGRD_742 | TGRD_163 | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | 0.944 |
TGRD_742 | pyrB | TGRD_742 | TGRD_748 | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.955 |
TGRD_742 | pyrC | TGRD_742 | TGRD_747 | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.955 |
TGRD_742 | pyrD | TGRD_742 | TGRD_743 | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Dihydroorotate dehydrogenase catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.983 |
TGRD_742 | pyrE | TGRD_742 | TGRD_741 | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.990 |