Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGRD_320Conserved hypothetical protein. (439 aa)    
Predicted Functional Partners:
TGRD_004
DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.944
TGRD_321
5-formyltetrahydrofolate cyclo-ligase; MTHFS; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
       0.793
rny
Putative HD superfamily hydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
       0.774
TGRD_712
DNA polymerase III epsilon subunit.
   
 
  0.741
TGRD_025
DNA polymerase III subunit alpha.
   
 
  0.739
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
     
  0.737
TGRD_361
Single-stranded DNA-binding protein.
     
  0.737
TGRD_364
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
     
  0.737
TGRD_369
DNA polymerase III delta subunit.
     
  0.737
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
  0.736
Your Current Organism:
uncultured Termite group 1 bacterium phylotype
NCBI taxonomy Id: 471821
Other names: u. Termite group 1 bacterium phylotype Rs-D17, uncultured Termite group 1 bacterium phylotype Rs-D17
Server load: low (8%) [HD]