STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_0533PFAM: regulatory protein IclR; Transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: oca:OCAR_6782 transcriptional regulator, IclR family. (247 aa)    
Predicted Functional Partners:
Tcur_0846
PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: aav:Aave_0116 IclR family transcriptional regulator.
  
     0.775
Tcur_0532
PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: mpt:Mpe_A3670 IclR family transcriptional regulator.
 
    
0.607
Tcur_0534
2-oxopent-4-enoate hydratase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: reu:Reut_B5691 4-oxalocrotonate decarboxylase.
  
  
 0.545
Tcur_0535
Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
       0.528
Tcur_0537
4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: ajs:Ajs_0225 4-oxalocrotonate decarboxylase.
  
  
 0.510
Tcur_0538
TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; KEGG: msl:Msil_1481 4-oxalocrotonate tautomerase.
       0.489
Tcur_0539
PFAM: Aldehyde Dehydrogenase; KEGG: ara:Arad_7263 betaine aldehyde dehydrogenase (BADH) protein.
     
 0.489
Tcur_0536
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
       0.487
Tcur_1845
KEGG: mxa:MXAN_2497 hypothetical protein.
 
      0.407
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.400
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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