STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_0579Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gme:Gmet_3382 heavy metal sensor signal transduction histidine kinase. (505 aa)    
Predicted Functional Partners:
Tcur_0578
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dat:HRM2_18670 two component transcriptional regulator (winged helix family protein).
 
 0.971
Tcur_2645
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mxa:MXAN_6734 response regulator/sensory box histidine kinase.
 
 0.941
Tcur_1461
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: glo:Glov_0588 two component transcriptional regulator, winged helix family.
 
 0.876
Tcur_3942
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: pol:Bpro_4150 response regulator receiver protein.
 
 
 0.873
Tcur_4043
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator.
 
 0.869
Tcur_0700
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator.
 
 0.866
Tcur_4122
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: scl:sce2434 two-component response regulator.
 
 0.859
Tcur_3363
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: tgr:Tgr7_1884 response regulator receiver protein.
 
 0.852
Tcur_1694
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: rlt:Rleg2_0704 two component transcriptional regulator, winged helix family.
 
 0.797
Tcur_3716
Putative integral membrane sensor protein; PFAM: MHYT domain protein; KEGG: mrd:Mrad2831_2786 multi-sensor signal transduction histidine kinase.
 
      0.785
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.