STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_0694PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: bpr:GBP346_A3376 oxidoreductase, short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)    
Predicted Functional Partners:
Tcur_1885
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce2387 non-ribosomal peptide synthetase.
    0.916
Tcur_2710
PFAM: AMP-dependent synthetase and ligase; KEGG: bxe:Bxe_C0851 acyl-CoA synthetase.
 
    0.866
Tcur_0102
PFAM: AMP-dependent synthetase and ligase; KEGG: ccs:CCNA_01017 acyl-CoA synthetase.
 
    0.812
Tcur_1178
KEGG: bph:Bphy_7198 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase.
      0.756
Tcur_1888
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: avi:Avi_9643 peptide synthetase.
  
 0.726
Tcur_0729
PFAM: iron-containing alcohol dehydrogenase; KEGG: GG20700 gene product from transcript GG20700- RA.
    
 0.697
Tcur_0359
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Non- ribosomal peptide synthetase; phosphopantetheine-binding; condensation domain protein; KEGG: pfl:PFL_3493 pyochelin synthetase E.
  
 0.695
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      0.688
Tcur_0696
Hypothetical protein.
       0.625
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.599
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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