STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_0699Histidine kinase; KEGG: dps:DP1886 PHO family two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (412 aa)    
Predicted Functional Partners:
Tcur_0700
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator.
 0.997
Tcur_2645
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mxa:MXAN_6734 response regulator/sensory box histidine kinase.
 
 
 0.966
Tcur_0698
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
 
   
 0.947
Tcur_4043
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator.
 
 0.921
Tcur_1461
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: glo:Glov_0588 two component transcriptional regulator, winged helix family.
 
 0.919
Tcur_4122
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: scl:sce2434 two-component response regulator.
 
 0.913
Tcur_4775
Multi-sensor signal transduction histidine kinase; KEGG: bbt:BBta_6262 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; response regulator receiver; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; ATP-binding region ATPase domain protein.
 
 
0.907
Tcur_0578
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dat:HRM2_18670 two component transcriptional regulator (winged helix family protein).
 
 0.901
Tcur_3716
Putative integral membrane sensor protein; PFAM: MHYT domain protein; KEGG: mrd:Mrad2831_2786 multi-sensor signal transduction histidine kinase.
      0.901
Tcur_3942
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: pol:Bpro_4150 response regulator receiver protein.
 
 
 0.886
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.