STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_0710Hypothetical protein. (259 aa)    
Predicted Functional Partners:
cysS
KEGG: gme:Gmet_0057 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.645
Tcur_0709
PFAM: homogentisate 12-dioxygenase; Cupin 2 conserved barrel domain protein; KEGG: shm:Shewmr7_2363 homogentisate 1,2- dioxygenase.
  
    0.502
Tcur_4452
PFAM: histone deacetylase superfamily; KEGG: gsu:GSU1222 histone deacetylase/AcuC/AphA family protein.
  
 0.441
Tcur_2863
TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: rsq:Rsph17025_1953 PfpI family intracellular peptidase.
  
 0.425
Tcur_3360
PFAM: ThiJ/PfpI domain protein; KEGG: bam:Bamb_1995 ThiJ/PfpI domain-containing protein.
  
 0.425
Tcur_0359
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Non- ribosomal peptide synthetase; phosphopantetheine-binding; condensation domain protein; KEGG: pfl:PFL_3493 pyochelin synthetase E.
  
  
 0.423
Tcur_0712
TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: gur:Gura_2796 RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
   0.423
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.413
Tcur_0586
SMART: AAA ATPase; KEGG: bid:Bind_2798 ATPase central domain- containing protein.
   
 0.405
Tcur_1592
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: met:M446_1988 ATPase central domain- containing protein.
   
 0.405
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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