STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_0803PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sat:SYN_01297 cold shock protein. (66 aa)    
Predicted Functional Partners:
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
  
 0.662
Tcur_2545
PFAM: helicase domain protein; SNF2-related protein; SMART: helicase domain protein; DEAD-like helicase; KEGG: sfu:Sfum_3846 helicase domain protein.
  
 0.590
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 
 0.537
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
 
 0.524
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.518
rpmJ
TIGRFAM: ribosomal protein L36; PFAM: ribosomal protein L36; KEGG: scl:sce7940 50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
   
 
 0.512
rpmE
Ribosomal protein L31; Binds the 23S rRNA.
  
 
 0.503
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
   0.498
rpsB
TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: pca:Pcar_1921 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.481
rplQ
TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; KEGG: geo:Geob_3598 ribosomal protein L17.
   
   0.467
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.