STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_0881Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; KEGG: afw:Anae109_0915 two component LuxR family transcriptional regulator. (266 aa)    
Predicted Functional Partners:
Tcur_2489
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; SMART: helix-turn-helix domain protein; KEGG: scl:sce8724 transcriptional regulator.
    
 
 0.687
Tcur_2958
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: xca:xccb100_4098 putative two-component system sensor kinase, ATP-binding region.
 
 
 0.607
Tcur_1623
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sml:Smlt0366 putative transmembrane sensor histidine kinase transcriptional regulatory protein.
 
 
 0.528
Tcur_2232
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
 
 
 0.498
Tcur_3934
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: pol:Bpro_4297 PAS/PAC sensor signal transduction histidine kinase.
 
 
 0.495
Tcur_0883
PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA1206 putative acetyl-coenzyme A synthetase.
     
 0.493
Tcur_4728
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: smt:Smal_0257 integral membrane sensor signal transduction histidine kinase.
 
 
 0.478
Tcur_0882
Hypothetical protein.
       0.476
Tcur_2769
PFAM: histidine kinase dimerisation and phosphoacceptor region; KEGG: xcv:XCV4087 two-component system sensor kinase.
 
 
 0.475
Tcur_2846
PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: scl:sce5432 putative two-component system sensor kinase.
 
 
 0.473
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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