STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_1107TIGRFAM: GTP-binding protein TypA; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: sfu:Sfum_2868 GTP-binding protein TypA. (617 aa)    
Predicted Functional Partners:
Tcur_2866
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
  
  
 0.841
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
  
 0.818
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
    0.749
rpsI
PFAM: ribosomal protein S9; KEGG: rsh:Rsph17029_1650 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
    0.660
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
   
  
 0.655
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.648
Tcur_1324
Hypothetical protein; KEGG: hha:Hhal_1736 putative ABC transporter.
  
  
 0.643
der
Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.643
Tcur_2321
PFAM: DSH domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: Os11g0176200; hypothetical protein.
      
 0.639
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
 
    0.637
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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