STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_1124PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: dvm:DvMF_2540 response regulator receiver protein. (165 aa)    
Predicted Functional Partners:
Tcur_1125
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: dal:Dalk_3400 histidine kinase.
 
 0.987
Tcur_1126
PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: response regulator receiver; protein phosphatase 2C domain protein; KEGG: dvm:DvMF_2541 multi-sensor signal transduction histidine kinase.
 
   
 0.970
Tcur_4775
Multi-sensor signal transduction histidine kinase; KEGG: bbt:BBta_6262 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; response regulator receiver; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; ATP-binding region ATPase domain protein.
 
 
 0.709
Tcur_4776
Multi-sensor hybrid histidine kinase; KEGG: reu:Reut_B4539 response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; response regulator receiver; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase A domain protein; response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein.
 
 
 0.645
Tcur_1123
TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: afw:Anae109_2602 succinate dehydrogenase/fumarate reductase cytochrome b subunit.
  
    0.538
Tcur_2644
GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; KEGG: mxa:MXAN_6735 sensor histidine kinase/response regulator.
 
 
 0.532
Tcur_2645
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mxa:MXAN_6734 response regulator/sensory box histidine kinase.
 
 
 
 0.516
Tcur_1460
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: lch:Lcho_2475 histidine kinase.
 
 
 0.514
Tcur_1122
KEGG: scl:sce6554 succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
  
    0.510
Tcur_1606
Putative PAS/PAC sensor protein; KEGG: met:M446_3558 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; PAS domain containing protein.
 
 
 0.503
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.