STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_1191Hypothetical protein. (171 aa)    
Predicted Functional Partners:
Tcur_3459
Hypothetical protein.
  
     0.767
Tcur_4493
PFAM: protein of unknown function DUF185; KEGG: lch:Lcho_0104 hypothetical protein.
  
     0.767
nuoI
4Fe-4S ferredoxin iron-sulfur binding domain protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
     0.686
Tcur_1192
Citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; KEGG: rhi:NGR_c26230 putative citrate lyase; Belongs to the HpcH/HpaI aldolase family.
       0.615
Tcur_1994
Putative transmembrane anti-sigma factor; KEGG: acp:A2cp1_0253 Fe-S oxidoreductase.
  
     0.605
Tcur_0095
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: mch:Mchl_3604 signal transduction histidine kinase.
  
     0.580
Tcur_1189
PFAM: protein of unknown function DUF1003; KEGG: pfs:PFLU4784 hypothetical protein.
       0.580
Tcur_1190
PFAM: MgtE intracellular region; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: gur:Gura_2041 MgtE intracellular region.
       0.579
Tcur_0119
KEGG: mno:Mnod_5591 hypothetical protein.
  
     0.556
Tcur_4275
Hypothetical protein; KEGG: rpc:RPC_0431 nitrous oxide metabolic protein.
  
     0.515
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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