STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_1429PFAM: PBS lyase HEAT domain protein repeat- containing protein; KEGG: hypothetical protein. (418 aa)    
Predicted Functional Partners:
Tcur_0780
PFAM: Heat shock protein 70; KEGG: mxa:MXAN_3192 chaperone protein DnaK.
  
   
 0.589
Tcur_3943
PFAM: integrase family protein; KEGG: pzu:PHZ_c3335 integrase/recombinase XerC.
 
   
 0.557
Tcur_4563
PFAM: chitin-binding domain 3 protein; KEGG: pae:PA0852 chitin-binding protein CbpD precursor.
  
     0.534
Tcur_2421
PFAM: Abortive infection protein; KEGG: cak:Caul_4749 abortive infection protein.
 
     0.532
Tcur_0374
Putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
     0.510
Tcur_1738
PFAM: glycoside hydrolase family 6; KEGG: mxa:MXAN_4837 endoglucanase; Belongs to the glycosyl hydrolase family 6.
  
     0.504
Tcur_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.491
Tcur_1512
PFAM: NmrA family protein; KEGG: aav:Aave_1295 NmrA family protein.
 
     0.473
Tcur_0072
KEGG: esa:ESA_pESA3p05539 hypothetical protein.
  
     0.471
Tcur_0446
PFAM: extracellular solute-binding protein family 1; KEGG: pmy:Pmen_3447 extracellular solute-binding protein.
  
     0.456
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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