STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB-2Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (290 aa)    
Predicted Functional Partners:
Tcur_1522
PFAM: Luciferase-like monooxygenase; KEGG: bja:bll6902 hypothetical protein.
       0.778
Tcur_2008
PFAM: helix-turn-helix HxlR type; KEGG: scl:sce2380 putative transcriptional regulator.
  
  
 0.710
Tcur_0296
PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; KEGG: sml:Smlt3523 putative valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.676
Tcur_0396
Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: ank:AnaeK_3118 glutamate dehydrogenase (NADP(+)); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.676
Tcur_1808
TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: hypothetical protein.
  
    0.628
Tcur_4461
TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: hypothetical protein.
  
    0.628
Tcur_2093
PFAM: phosphate acetyl/butaryl transferase; DRTGG domain protein; KEGG: net:Neut_1995 phosphate acetyltransferase.
  
  
 0.627
Tcur_1516
PFAM: Tetratricopeptide TPR_4; KEGG: scl:sce5225 protein kinase.
   
    0.626
Tcur_2333
PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: scl:sce5626 leucine responsive regulatory protein.
  
    0.622
Tcur_2223
Putative transcriptional regulator; PFAM: regulatory protein ArsR; regulatory protein MarR; HMG-I and HMG-Y DNA-binding domain protein; KEGG: bpd:BURPS668_A1579 hypothetical protein.
   
    0.614
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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