STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_1903KEGG: afw:Anae109_2319 glutamine amidotransferase class-II. (291 aa)    
Predicted Functional Partners:
Tcur_1904
PFAM: LmbE family protein; KEGG: sse:Ssed_4036 hypothetical protein.
       0.548
egtD
Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
  
  
 0.540
Tcur_1902
PFAM: band 7 protein; SMART: band 7 protein; KEGG: sml:Smlt1263 putative transmembrane protein.
       0.527
Tcur_1900
Hypothetical protein.
       0.526
Tcur_1901
KEGG: xac:XAC1234 hypothetical protein.
       0.526
egtB
Protein of unknown function DUF323; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
 
  
 0.458
Tcur_4260
PFAM: aminoglycoside phosphotransferase; KEGG: mrd:Mrad2831_4452 aminoglycoside phosphotransferase.
  
     0.448
Tcur_0285
Hypothetical protein.
 
     0.431
egtA
Glutamate/cysteine ligase family protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
 
    0.419
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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