STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_2012PFAM: Ppx/GppA phosphatase; KEGG: gsu:GSU2559 exopolyphosphatase, putative. (311 aa)    
Predicted Functional Partners:
Tcur_1039
PFAM: Ppx/GppA phosphatase; KEGG: scl:sce1705 hypothetical protein.
  
  
0.953
Tcur_2116
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.921
Tcur_4101
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: bja:bll5065 GTP pyrophosphokinase.
  
 
 0.915
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.899
Tcur_2011
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: short chain dehydrogenase/reductase family.
     
 0.528
Tcur_2013
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; WD40 domain protein beta Propeller; aminoglycoside phosphotransferase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: pag:PLES_00751 serine/threonine protein kinase PpkA.
     
 0.489
Tcur_2108
PFAM: protein of unknown function DUF28; KEGG: gme:Gmet_0743 hypothetical protein.
     
 0.466
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.444
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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