STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_2044Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: dvl:Dvul_1630 anti-sigma-factor antagonist. (126 aa)    
Predicted Functional Partners:
Tcur_4775
Multi-sensor signal transduction histidine kinase; KEGG: bbt:BBta_6262 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; response regulator receiver; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; histidine kinase A domain protein; GAF domain protein; ATP-binding region ATPase domain protein.
 
 
 0.916
Tcur_0838
Putative PAS/PAC sensor protein; KEGG: gme:Gmet_1230 serine phosphatase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; PAS domain containing protein.
 
 
 0.618
Tcur_3691
TIGRFAM: RNA polymerase sigma-70 factor, sigma- B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 4 domain protein; KEGG: aeh:Mlg_2516 RNA polymerase, sigma 70 subunit, RpoD.
 
 
 0.610
Tcur_4776
Multi-sensor hybrid histidine kinase; KEGG: reu:Reut_B4539 response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; ATP- binding region ATPase domain protein; response regulator receiver; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase A domain protein; response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein.
 
 
 0.608
Tcur_3555
KEGG: dvm:DvMF_2963 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein.
  
  
 0.607
Tcur_1606
Putative PAS/PAC sensor protein; KEGG: met:M446_3558 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; PAS domain containing protein.
 
 
 0.603
Tcur_0315
PFAM: ATP-binding region ATPase domain protein; KEGG: sil:SPO3410 anti-sigma B factor, putative.
 
   0.599
Tcur_4827
Putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
   0.589
Tcur_3632
PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: rlt:Rleg2_0075 signal transduction histidine kinase.
 
   0.572
Tcur_2814
Putative PAS/PAC sensor protein; PFAM: Stage II sporulation E family protein; GAF domain protein; PAS fold-4 domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; PAS domain containing protein; KEGG: gme:Gmet_2062 serine phosphatase.
 
 
 0.554
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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