STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_2159KEGG: bmu:Bmul_0540 3-methyladenine DNA glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase; PFAM: methylpurine-DNA glycosylase (MPG); Belongs to the DNA glycosylase MPG family. (209 aa)    
Predicted Functional Partners:
tadA
CMP/dCMP deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.726
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: pfo:Pfl01_2852 argininosuccinate lyase.
       0.702
Tcur_4133
Transcriptional regulator, AraC family; PFAM: Ada metal-binding domain protein; AlkA domain protein; HhH-GPD family protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; HhH-GPD family protein; KEGG: scl:sce6205 putative regulatory protein Ada.
  
  
 0.537
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
  
 0.428
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: ade:Adeh_1971 phenylalanyl-tRNA synthetase beta subunit.
  
    0.406
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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