STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_2385PFAM: aminotransferase class V; KEGG: acp:A2cp1_4498 aminotransferase class V. (357 aa)    
Predicted Functional Partners:
Tcur_2229
TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: ade:Adeh_0847 SUF system FeS assembly protein.
 
 
 0.975
Tcur_2227
FeS assembly ATPase SufC; KEGG: ftm:FTM_0976 SufS activator complex, SufC subunit; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.810
Tcur_2224
TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: afw:Anae109_0903 cysteine desulfurase activator complex subunit SufB.
 
 
 0.775
Tcur_2225
TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: mxa:MXAN_1155 FeS assembly protein SufD.
  
 
 0.735
Tcur_2386
Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: aav:Aave_0303 LysR family transcriptional regulator.
       0.550
egtD
Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
  
  
 0.538
Tcur_2849
PFAM: Endonuclease/exonuclease/phosphatase; KEGG: smd:Smed_4045 endonuclease/exonuclease/phosphatase.
  
 
   0.519
Tcur_3976
Hypothetical protein; KEGG: pna:Pnap_1576 iron-sulfur cluster assembly accessory protein.
 
 
 0.480
Tcur_2230
PFAM: protein of unknown function DUF59; KEGG: bmn:BMA10247_1695 hypothetical protein.
  
  
 0.444
egtA
Glutamate/cysteine ligase family protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
  
  
 0.433
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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