STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_2464PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: ajs:Ajs_1713 alpha/beta hydrolase domain- containing protein. (317 aa)    
Predicted Functional Partners:
Tcur_1834
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: pae:PA2097 flavin-binding monooxygenase.
  
 0.929
Tcur_3835
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bac:BamMC406_4526 flavin-containing monooxygenase FMO.
  
 0.929
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
 
    0.901
Tcur_2742
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: bph:Bphy_0360 alpha/beta hydrolase domain- containing protein.
  
     0.759
Tcur_2465
PFAM: peptidase C26; glutamine amidotransferase class-I; KEGG: ank:AnaeK_0082 peptidase C26.
       0.741
Tcur_1886
TIGRFAM: amino acid adenylation domain protein; non- ribosomal peptide synthase; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: scl:sce8257 non-ribosomal peptide synthetase.
  
 
 0.733
Tcur_1051
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: hch:HCH_01563 esterase/lipase.
  
     0.726
Tcur_4412
NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
    
 
 0.442
Tcur_1570
Hypothetical protein.
   
 0.432
Tcur_4414
TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: Ndufv2; NADH dehydrogenase (ubiquinone) flavoprotein 2; K03943 NADH dehydrogenase (ubiquinone) flavoprotein 2.
    
   0.412
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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