STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_2617PFAM: aminotransferase class I and II; KEGG: aeh:Mlg_2554 aminotransferase. (446 aa)    
Predicted Functional Partners:
Tcur_2866
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
  
 
 0.958
argG
KEGG: hypothetical protein; K01940 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.924
Tcur_4358
PFAM: aminotransferase class I and II; KEGG: ppd:Ppro_2189 aminotransferase, class I and II.
  
  
 
0.922
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.920
Tcur_4016
TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: afw:Anae109_0887 delta-1-pyrroline-5- carboxylate dehydrogenase.
   
 0.919
Tcur_0121
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: ade:Adeh_1779 prephenate dehydratase.
 
 
 0.918
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.916
Tcur_1062
KEGG: 4-hydroxyphenylpyruvate dioxygenase, putative; K00457 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
   
 
 0.913
Tcur_3717
Tyrosine 3-monooxygenase; PFAM: aromatic amino acid hydroxylase; KEGG: hypothetical protein.
   
 
 0.913
Tcur_4925
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mch:Mchl_0204 pyridoxal-5'-phosphate- dependent protein beta subunit.
   
 0.911
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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