STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (273 aa)    
Predicted Functional Partners:
trpB-2
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 0.999
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: afw:Anae109_0373 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
 
 0.999
trpB
Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.996
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.992
Tcur_0369
PFAM: Chorismate binding-like; KEGG: pau:PA14_54940 putative siderophore biosynthesis enzyme.
 
  
 0.981
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: ppd:Ppro_1292 N-(5'- phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
  
 0.977
Tcur_2476
TIGRFAM: anthranilate synthase; PFAM: Chorismate binding-like; glutamine amidotransferase class-I; Anthranilate synthase component I domain protein; KEGG: scl:sce5044 anthranilate synthase.
 
  
 0.976
Tcur_0062
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cak:Caul_2776 anthranilate synthase component II.
 
  
 0.967
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.950
Tcur_2045
PFAM: Chorismate binding-like; KEGG: met:M446_0053 para-aminobenzoate synthase, subunit I.
 
  
 0.924
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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