Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ureB-2KEGG: smd:Smed_2386 urease subunit beta; TIGRFAM: urease, beta subunit; PFAM: Urease beta subunit; Belongs to the urease beta subunit family. (103 aa)    
Predicted Functional Partners:
ureC
KEGG: bov:BOV_1314 urease subunit alpha; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Amidohydrolase 3.
 0.999
Tcur_2068
KEGG: bfl:Bfl525 urease subunit gamma; TIGRFAM: urease, gamma subunit; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family.
 0.999
ureA
KEGG: mrd:Mrad2831_2863 urease, gamma subunit; TIGRFAM: urease, gamma subunit; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family.
 0.999
ureC-2
KEGG: met:M446_2211 urease, alpha subunit; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Amidohydrolase 3.
 0.999
ureD-2
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.959
ureG-2
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 0.950
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.935
ureF-2
Conserved hypothetical protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.911
ureB
Urease, beta subunit; KEGG: mpo:Mpop_1135 urease, gamma subunit; TIGRFAM: urease, beta subunit; PFAM: Urease beta subunit; Belongs to the urease beta subunit family.
  
  
 
0.905
Tcur_3814
PFAM: amidinotransferase; KEGG: aeh:Mlg_0130 amidinotransferase.
     
  0.900
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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