STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_3703PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; RimK domain protein ATP-grasp; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mxa:MXAN_5595 acetyl-CoA carboxylase, biotin carboxylase. (444 aa)    
Predicted Functional Partners:
Tcur_1637
PFAM: carboxyl transferase; KEGG: dal:Dalk_3780 propionyl-CoA carboxylase.
 
 0.997
Tcur_1213
PFAM: carboxyl transferase; KEGG: acetyl-coA carboxylase; K01959 pyruvate carboxylase subunit A.
 
 0.994
Tcur_3702
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: mxa:MXAN_5594 biotin/lipoic acid binding domain-containing protein.
  
 0.994
Tcur_1977
Methylcrotonoyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: bpt:Bpet0056 putative methylcrotonyl-CoA carboxylase subunit.
 
 0.977
Tcur_2771
PFAM: carboxyl transferase; KEGG: ade:Adeh_0250 carboxyl transferase.
 
 0.977
Tcur_4130
PFAM: carboxyl transferase; KEGG: ade:Adeh_0250 carboxyl transferase.
 
 0.977
Tcur_1862
PFAM: carboxyl transferase; biotin/lipoyl attachment domain-containing protein; KEGG: rpi:Rpic_2413 carbamoyl-phosphate synthase L chain ATP-binding.
 
 0.975
Tcur_0221
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: csa:Csal_1600 [acyl-carrier-protein] S- malonyltransferase.
 
 
 0.974
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.966
Tcur_1641
KEGG: bpd:BURPS668_2791 malonyl CoA-acyl carrier protein transacylase.
 
 
 0.954
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
Server load: low (18%) [HD]