STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_4042Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: gbm:Gbem_2673 heavy metal sensor signal transduction histidine kinase. (594 aa)    
Predicted Functional Partners:
Tcur_4043
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator.
 0.993
Tcur_2645
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mxa:MXAN_6734 response regulator/sensory box histidine kinase.
 
 0.932
Tcur_4041
Hypothetical protein.
    0.888
Tcur_0700
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator.
 
 0.862
Tcur_3942
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: pol:Bpro_4150 response regulator receiver protein.
 
 
 0.835
Tcur_3363
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: tgr:Tgr7_1884 response regulator receiver protein.
 
 0.833
Tcur_4122
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: scl:sce2434 two-component response regulator.
 
 0.833
Tcur_1461
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: glo:Glov_0588 two component transcriptional regulator, winged helix family.
 
 0.819
Tcur_0578
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: dat:HRM2_18670 two component transcriptional regulator (winged helix family protein).
 
 0.815
Tcur_1694
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: rlt:Rleg2_0704 two component transcriptional regulator, winged helix family.
 
 0.798
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.