STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_4464PFAM: Xylose isomerase domain protein TIM barrel; KEGG: glo:Glov_2906 xylose isomerase domain protein TIM barrel. (294 aa)    
Predicted Functional Partners:
Tcur_4463
PFAM: regulatory protein TetR; KEGG: mlo:mlr3851 TetR family transcriptional regulator.
       0.789
Tcur_0204
Hypothetical protein.
  
     0.584
Tcur_3565
PFAM: Methionine synthase vitamin-B12 independent; KEGG: dal:Dalk_5194 hypothetical protein.
 
     0.568
Tcur_1740
KEGG: dal:Dalk_1860 hypothetical protein.
  
    0.566
Tcur_3868
KEGG: dal:Dalk_1860 hypothetical protein.
  
    0.566
Tcur_4462
Hypothetical protein; KEGG: dol:Dole_0811 ABC-2 type transporter.
       0.559
Tcur_4465
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: mno:Mnod_5725 methyltransferase type 11.
       0.544
Tcur_4429
PFAM: ResB family protein; KEGG: dal:Dalk_1265 ResB family protein.
 
     0.536
Tcur_1629
Hypothetical protein.
  
     0.533
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.524
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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