STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panD-2Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (150 aa)    
Predicted Functional Partners:
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 0.998
Tcur_4485
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.926
Tcur_3380
PFAM: aminotransferase class-III; KEGG: hypothetical protein; K00827 alanine-- glyoxylate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.912
Tcur_0851
PFAM: Aldehyde Dehydrogenase; KEGG: scl:sce5007 putative aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.
     
 0.905
Tcur_1827
PFAM: Aldehyde Dehydrogenase; KEGG: bur:Bcep18194_B1170 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
 0.905
Tcur_2580
PFAM: Aldehyde Dehydrogenase; KEGG: bur:Bcep18194_B1170 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
 0.905
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.905
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
  
  
 
0.902
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
  
 0.896
Tcur_2617
PFAM: aminotransferase class I and II; KEGG: aeh:Mlg_2554 aminotransferase.
    
 0.814
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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