STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_4955Peptidoglycan glycosyltransferase; PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: avi:Avi_0305 penicillin-binding protein. (747 aa)    
Predicted Functional Partners:
Tcur_2919
PFAM: DivIVA family protein; KEGG: met:M446_2611 translation initiation factor IF-2.
   
 
 0.843
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
 
   
 0.774
Tcur_2927
TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: afw:Anae109_3883 cell division protein FtsW; Belongs to the SEDS family.
 
 
 
 0.726
Tcur_2932
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: gme:Gmet_0406 penicillin-binding protein, transpeptidase.
 
 
 
 0.693
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
   
 0.675
Tcur_1543
TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: bba:Bd2461 rod shape-determining protein; Belongs to the SEDS family.
 
 
 
 0.672
mraY
phospho-N-acetylmuramoyl-pentapeptide-transferas e; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.666
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.629
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
   
 0.619
Tcur_4002
PFAM: NTF2 domain protein transpeptidase; penicillin-binding protein transpeptidase; KEGG: mxa:MXAN_7139 putative penicillin-binding protein.
 
 
 
 0.619
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.