STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcur_4974Hypothetical protein. (205 aa)    
Predicted Functional Partners:
Tcur_4181
PFAM: AIG2 family protein; KEGG: C7orf24; chromosome 7 open reading frame 24; K00682 gamma-glutamylcyclotransferase.
  
     0.746
Tcur_3050
PFAM: metallophosphoesterase; KEGG: sit:TM1040_3062 metallophosphoesterase.
  
     0.559
Tcur_4940
Hypothetical protein.
  
     0.520
Tcur_4975
Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein.
       0.509
Tcur_4973
PFAM: extracellular solute-binding protein family 5; KEGG: ara:Arad_12429 extracellular solute-binding protein.
       0.499
Tcur_1875
PFAM: amino acid-binding ACT domain protein.
  
     0.473
ddl-2
D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
       0.466
Tcur_3017
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: eca:ECA3391 putative prophage regulatory ptotein.
  
     0.452
Tcur_0663
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bur:Bcep18194_A5003 XRE family transcriptional regulator.
  
     0.445
whiB-6
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.437
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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