STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcav_1271PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; DJ-1/PfpI family. (317 aa)    
Predicted Functional Partners:
Bcav_3518
Transcriptional regulator, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family.
 
 
 0.647
Bcav_2070
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
 
 
 0.646
Bcav_0066
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain.
 
 
 0.618
Bcav_0072
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
 
 
 0.584
Bcav_1270
Hypothetical protein.
       0.544
Bcav_1816
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
 
 
 0.489
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.465
Bcav_1223
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain.
 
 
0.462
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
 
 0.411
Your Current Organism:
Beutenbergia cavernae
NCBI taxonomy Id: 471853
Other names: B. cavernae DSM 12333, Beutenbergia cavernae DSM 12333, Beutenbergia cavernae str. DSM 12333, Beutenbergia cavernae strain DSM 12333
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.