STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcav_1379Urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain. (282 aa)    
Predicted Functional Partners:
Bcav_1378
PFAM: Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370.
 
 0.999
Bcav_1377
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
 0.997
gatA
glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
    
 0.920
Bcav_1137
Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Biotin carboxylase C-terminal domain; Biotin-requiring enzyme; Carbamoyl-phosphate synthase L chain, N-terminal domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain.
 
  
 0.917
Bcav_3851
PFAM: ATP-grasp domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme; Biotin carboxylase C-terminal domain.
 
  
 0.917
Bcav_1376
Conserved hypothetical protein.
       0.773
Bcav_1380
Conserved hypothetical protein.
       0.768
Bcav_2856
Conserved hypothetical protein.
  
  
 0.723
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
       0.655
Bcav_3669
PFAM: Amidase; Belongs to the amidase family.
    
 0.655
Your Current Organism:
Beutenbergia cavernae
NCBI taxonomy Id: 471853
Other names: B. cavernae DSM 12333, Beutenbergia cavernae DSM 12333, Beutenbergia cavernae str. DSM 12333, Beutenbergia cavernae strain DSM 12333
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.