STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcav_1769Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain. (191 aa)    
Predicted Functional Partners:
Bcav_3841
Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain.
  
     0.767
Bcav_2027
Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain.
  
     0.765
Bcav_0204
Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain.
  
     0.756
Bcav_0541
Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain.
  
     0.750
Bcav_1770
Protein of unknown function DUF187; PFAM: Uncharacterised BCR, COG1649; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
       0.522
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.431
Bcav_0271
Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain.
 
     0.408
Your Current Organism:
Beutenbergia cavernae
NCBI taxonomy Id: 471853
Other names: B. cavernae DSM 12333, Beutenbergia cavernae DSM 12333, Beutenbergia cavernae str. DSM 12333, Beutenbergia cavernae strain DSM 12333
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