STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (888 aa)    
Predicted Functional Partners:
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.964
Bcav_2215
PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.944
Bcav_0076
PFAM: Pyruvate phosphate dikinase, PEP/pyruvate binding domain; PEP-utilising enzyme, mobile domain.
     
 0.938
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.930
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.917
eno-2
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.917
mqo
PFAM: FAD dependent oxidoreductase; TIGRFAM: malate:quinone-oxidoreductase.
     
 0.915
Bcav_2770
Pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; PEP-utilising enzyme, mobile domain; TIGRFAM: pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.914
Bcav_2217
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.868
Bcav_1130
PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
     
 0.861
Your Current Organism:
Beutenbergia cavernae
NCBI taxonomy Id: 471853
Other names: B. cavernae DSM 12333, Beutenbergia cavernae DSM 12333, Beutenbergia cavernae str. DSM 12333, Beutenbergia cavernae strain DSM 12333
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.