STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcav_3609PFAM: MerR family regulatory protein; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; MerR, DNA binding. (288 aa)    
Predicted Functional Partners:
Bcav_3610
PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
       0.777
Bcav_0667
PFAM: MerR, DNA binding; MerR family regulatory protein.
  
     0.673
Bcav_3611
Putative fructose transport system kinase.
       0.628
Bcav_3612
PFAM: Protein of unknown function (DUF718).
       0.628
Bcav_0052
PFAM: Uncharacterized conserved protein (DUF2174).
 
    0.521
Bcav_1855
PFAM: Glutamine synthetase, beta-Grasp domain; Glutamine synthetase, catalytic domain; TIGRFAM: glutamine synthetase, type I.
 
 
 0.501
dnaJ
Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...]
  
 
 0.498
Bcav_3707
PFAM: DnaJ C terminal region; DnaJ domain.
  
 
 0.498
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.432
Bcav_1849
PFAM: Glutamine synthetase, beta-Grasp domain; Glutamine synthetase, catalytic domain; TIGRFAM: glutamine synthetase, type I.
  
 
 0.406
Your Current Organism:
Beutenbergia cavernae
NCBI taxonomy Id: 471853
Other names: B. cavernae DSM 12333, Beutenbergia cavernae DSM 12333, Beutenbergia cavernae str. DSM 12333, Beutenbergia cavernae strain DSM 12333
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.