STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dfer_1612PFAM: bifunctional deaminase-reductase domain protein; KEGG: saq:Sare_1206 deaminase-reductase domain- containing protein. (206 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.782
Dfer_0754
PFAM: bifunctional deaminase-reductase domain protein; KEGG: chu:CHU_0402 dihydrofolate reductase (DHFR).
  
     0.693
Dfer_1784
PFAM: bifunctional deaminase-reductase domain protein; KEGG: rha:RHA1_ro06214 reductase.
  
     0.690
Dfer_1347
PFAM: bifunctional deaminase-reductase domain protein; KEGG: cbe:Cbei_2234 bifunctional deaminase- reductase domain protein.
  
     0.652
Dfer_0824
PFAM: bifunctional deaminase-reductase domain protein; KEGG: sen:SACE_6648 bifunctional deaminase- reductase-like protein.
  
     0.649
Dfer_2243
PFAM: bifunctional deaminase-reductase domain protein; KEGG: chu:CHU_1753 dihydrofolate reductase.
  
     0.636
Dfer_1448
PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: fjo:Fjoh_1708 activator of HSP90 ATPase 1 family protein.
 
      0.611
Dfer_0283
KEGG: rha:RHA1_ro06729 hypothetical protein.
 
      0.591
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.565
Dfer_1613
PFAM: Kelch repeat-containing protein; KEGG: pdi:BDI_2349 hypothetical protein.
       0.535
Your Current Organism:
Dyadobacter fermentans
NCBI taxonomy Id: 471854
Other names: D. fermentans DSM 18053, Dyadobacter fermentans DSM 18053, Dyadobacter fermentans str. DSM 18053, Dyadobacter fermentans strain DSM 18053
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.