STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purDKEGG: chu:CHU_0296 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. (429 aa)    
Predicted Functional Partners:
purN
Formyl transferase domain protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 0.999
Dfer_4043
Amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; KEGG: chu:CHU_2612 amidophosphoribosyltransferase.
 0.998
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
 0.997
purC
PFAM: SAICAR synthetase; KEGG: chu:CHU_1912 phosphoribosylaminoimidazole- succinocarboxamide synthase.
 
 0.997
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
 0.997
purH
IMP cyclohydrolase; KEGG: chu:CHU_3309 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region.
 
 
 0.978
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
 
  
 0.969
Dfer_4180
Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; KEGG: bth:BT_4211 putative phosphoribosylformylglycinamidine cyclo-ligase.
 
  
 0.964
Dfer_3669
TIGRFAM: formyltetrahydrofolate deformylase; PFAM: formyl transferase domain protein; KEGG: wsu:WS1475 formyltetrahydrofolate deformylase.
 
   
 0.960
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.941
Your Current Organism:
Dyadobacter fermentans
NCBI taxonomy Id: 471854
Other names: D. fermentans DSM 18053, Dyadobacter fermentans DSM 18053, Dyadobacter fermentans str. DSM 18053, Dyadobacter fermentans strain DSM 18053
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.