STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (434 aa)    
Predicted Functional Partners:
murE
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
0.997
mraY
phospho-N-acetylmuramoyl-pentapeptide-transferas e; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
 0.992
Dfer_4937
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.959
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.954
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.936
Dfer_4988
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
  
0.929
Dfer_0515
TIGRFAM: cyanophycin synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; RimK domain protein ATP-grasp; phosphoribosylglycinamide synthetase; KEGG: gvi:gll4326 cyanophycin synthetase; Belongs to the MurCDEF family.
  
  
 0.891
Dfer_5594
TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; histidinol-phosphate phosphatase family protein; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tbd:Tbd_0741 histidinol-phosphate phosphatase.
      0.834
Dfer_3489
PFAM: cell cycle protein; KEGG: aas:Aasi_0815 hypothetical protein; Belongs to the SEDS family.
 
 
 0.833
Dfer_3521
Peptidoglycan glycosyltransferase; KEGG: chu:CHU_2746 cell division protein, penicillin-binding protein; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; SMART: PASTA domain containing protein.
 
  
 0.833
Your Current Organism:
Dyadobacter fermentans
NCBI taxonomy Id: 471854
Other names: D. fermentans DSM 18053, Dyadobacter fermentans DSM 18053, Dyadobacter fermentans str. DSM 18053, Dyadobacter fermentans strain DSM 18053
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