STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dfer_5000PFAM: transcriptional coactivator/pterin dehydratase; KEGG: chu:CHU_3388 pterin-4-alpha-carbinolamine dehydratase. (78 aa)    
Predicted Functional Partners:
Dfer_2108
PFAM: aromatic amino acid hydroxylase; KEGG: reu:Reut_A3387 phenylalanine 4-monooxygenase.
 
 0.984
Dfer_4997
PFAM: inositol monophosphatase; KEGG: chu:CHU_3258 inositol-1-monophosphatase.
  
    0.817
rsmI
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.804
Dfer_4998
KEGG: sru:SRU_2357 hypothetical protein.
       0.789
Dfer_2106
PFAM: homogentisate 12-dioxygenase; KEGG: fjo:Fjoh_0728 homogentisate 1,2-dioxygenase.
  
  
 0.525
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.523
Dfer_5001
PFAM: OsmC family protein; KEGG: lbf:LBF_4142 redox protein, regulator of disulfide bond formation.
       0.494
Dfer_4996
KEGG: fjo:Fjoh_0486 metal-dependent hydrolase.
       0.477
Dfer_5003
PFAM: protein of unknown function UPF0126; KEGG: lbf:LBF_2554 hypothetical protein.
       0.473
Dfer_4995
Hypothetical protein.
       0.455
Your Current Organism:
Dyadobacter fermentans
NCBI taxonomy Id: 471854
Other names: D. fermentans DSM 18053, Dyadobacter fermentans DSM 18053, Dyadobacter fermentans str. DSM 18053, Dyadobacter fermentans strain DSM 18053
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.